Serum hscrp in hemorrhagic and ischaemic stroke: a diagnostic marker?

Ischemic stroke is the most common type of stroke and accounts for about 80%–85% of stroke cases last few decades. hsCRP is considered a marker of low-grade vascular inflammation, which contributes to the development and rupture of atheromatous plaque. hsCRP level when measured prior to the onset of clinical diseases may be an independent predictor of the first ischemic stroke. The present case control study was conducted in Gauhati Medical College & Hospital, Guwahati, Assam from February 2016 to February 2017. The case and control groups consisted of 50 patients diagnosed with cerebrovascular accident with duration of onset within 72 hours and age and sex-matched 50 healthy individuals respectively. Estimation of Serum hsCRP was done using Vitros 5600 Autoanalyzer. The values obtained were statistically analysed. In the Unpaired t test between control and case groups, the two-tailed P value for serum hsCRP was <0.0001 (extremely significant). The mean hsCRP was significantly higher (p=0.035) in haemorrhage cases than in infarct cases.Thus, we can conclude that hsCRP level is increased in both ischaemic and haemorrhagic stroke. Furthermore, it was seen that hsCRP was more increased in hemorrhagic stroke rather than in stroke due to infarct. Therefore, it can be suggested that hsCRP might be used in differentiating between the two types of stroke.