Lipid per-oxidation in type-2 diabetes mellitus patients

Author: 
Charu Bala Asthana

Lipid peroxidation is a process through which oxidants such as free radicals attack lipids specifically polyunsaturated fatty acids. From last four decades, an extensive literature regarding lipid peroxidation has shown its important role in cell biology and human health. The aldehyde degradation products of lipid peroxides are toxic to cells. Ferrous ion reacts with a lipid peroxide to generate the free radical that can propagate peroxidation reactions. The increase in free radical activity in type-2 diabetes mellitus with insulin resistance explain enhanced lipid peroxidation which may explain an important role in the complications of diabetes mellitus patients. The present study was conducted in CSSH, Meerut in the year 2008.100 controls & 100 T2DM patients of age 45-65 years were included for the study.

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DOI: 
http://dx.doi.org/10.24327/ijrsr.2023.1408.2424.1524
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Volume12