Mechanically ventilated patients experience many barriers while communicating their needs. It is important to develop alternative methods of communicating for those patients. The objectives of the present study were: to assess the communication and level of frustration among the selected patients, to assess the effectiveness of communication board on communication and level of frustration , to find correlation between communication and level of frustration, to find association between communication and level of frustration among patients. A quantitative research approach, true experimental design with a post test only control group design was adopted. A total sample size of 60 was selected by random sampling. Findings of the study showed that the communication board was effective in improving communication (t= 9.051, p = 0.001) and frustration (t= -6.604, p = 0.001) of mechanically ventilated post cardio thoracic surgery patients. There was a statistical significant strong negative correlation (r= -.543) between the communication and level of frustration. And there was no significant association between communication and level of frustration (p=0.05) with their selected baseline variables in both the experimental and control group. To conclude, communication board helped to improve communication and erase frustration of mechanically ventilated patients to some extent.