Introduction – Serum uric acid (SUA) has been considered as independent factor for cardiovascular disorders through various mechanisms.SUA also showed impact on parameters like body mass index, blood pressure and biochemical parameters like serum lipids.
Material & methods – This was cross sectional observational study carried out on 150 subjects by dividing them in group A,B and C. Group A were normotensives, group B were hypertensives not on antihypertensive (anti HTN) medication and group C were hypertensives on anti HTN medication for more than 6 months. We looked for effect of anti HTN medications on SUA levels and other parameters like blood pressure, body mass index and lipid profile. Statistical tests were applied by using Openepi software.
Result – Age was comparable among all groups. BMI showed significant reduction in group C. Decrease in SUA level in group C was highly significant. Serum triglyceride and HDL didn’t show reduction but serum cholesterol declined at significant level.
Conclusion- Anti HTN medication reduces SUA level which is raised in hypertension. Also, reducing blood pressure normalises body mass index and lipid profile.
Impact Factor
2022: 6.012
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