Background: Variceal bleeding accounts for 10-30% of all cases of upper gastrointestinal bleeding. Upper Gastro Intestinal Endoscopy is used to screen all cirrhotic patients at diagnosis for identification of varices at a high risk of bleeding with is invasive and costly.There are certain non-invasive techniques available to predict development of oesophageal varices. The objective of the study was to study the role of platelet count, splenic size in predicting the esophageal varices in cirrhotic patients. Materials & Methods: A cross sectional study was conducted in the department of General Medicine for a period of one year from November 2022 - October 2023. 50 patients who were admitted with cirrhotic liver disease, who underwent Upper Gastro Intestinal Endoscopy were included in the study. Results: The mean age of study participants was 60.32 ± 9.48 years with male predominance. Lower platelet count, higher values of Serum bilirubin, Serum Albumin, Prothromin Time, Spleen size were significantly associated with oesophageal varices. Conclusion: Lower platelet count was significantly associated with higher grade of oesophageal varices.