Spinal anaesthesia is the most established technique for lower limb surgeries. In cardiac patients, central neuraxial block and General anaesthesia can be catastrophic due to its deleterious effects. Use of peripheral nerve blocks provides better hemodynamic stability and pain management in high risk patients. We report a case of successful anaesthetic management of patient with very low ejection fraction and coronary artery diseaseposted for right below knee amputation under ultrasound guided nerve block.