Introduction: In recent years the prevalence of gestational diabetes mellitus is remarkably increased. Obesity is the most important risk factor for GDM. Abdominal obesity is associated with insulin resistance and metabolic syndrome. Maternal abdominal subcutaneous fat thickness is highly correlated with obesity and can be measured by ultrasonography. This study was done to find correlation between maternal ASCFT and development of GDM and to find a cut-off value of ASCFT for prediction of risk of developing GDM.
Material and method: This was a prospective observational study. 200 women included in the study were classified as normal (n=181) and with GDM (n=19) on the basis of DIPSI. Abdominal subcutaneous fat thickness was measured by ultrasonography. Data were evaluated statistically.
Results: Mean age of the women who developed GDM (27.47 ± 2.14 years) was significantly more. Receiver-operating characteristic curve analysis showed ASCFT above 15.2 mm predicted GDM with 100% sensitivity and 91.78% specificity and the risk of developing GDM was significantly high [odd ratio-117 (95% CI 14.9262-917.1130, p <0.0001)].
Conclusion: Measurement of abdominal subcutaneous fat thickness by ultrasonography at 16 -18 weeks may help to identify women at risk of developing GDM at 24-28 weeks.
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