Agriculture places a vital role in our day-today life.Due to many factors, agriculture has being diploiting. One such major factor is "pathogens", which infects the yield and affects the cultivation widely. Bacteria, fungi and virus are most commonly
infecting pathogens in plant. One such crises in wheat cultivation is wheat has been infected and affected by various diseases like "leaf rust, stem rust and yellow rust". Due to these disease, wheat cultivation has been widely affected. Since, wheat is an important grain, which is also used as an alternative source of rice, this problem should
be rectified in order to increase the wheat cultivation. Thus, researchers focused on increasing the stem rust disease resistance in wheat plant by cloning many disease resistance genes in wheat. But annotating the disease resistance gene from an whole wheat genome has become challenging job for the researchers.