Background: Dyspepsia is a frequent syndrome in our country, where there are restrictions to endoscopy and high prevalence of Helicobacter pylori (H. pylori) infection. The age indication for endoscopy has not been determined in our country. Establishment of this procedure for every dyspeptic patient may not be practical or cost effective.
Aim:To assess the endoscopic findings in uninvestigated dyspepsia syndrome, in tertiary care hospital of southern India.
Methods:Patients withuninvestigated dyspepsia, as per ROME III criteria, were screened from outpatients of gastroenterology department where they underwent esophagogastroduodenoscopy(OGD). Rapid Urease Test(RUT)was done in selected cases. Organic dyspepsia findings were analysed with different variables to verify statistically significant associations.
Results: Out of 516 patients enrolled, 500 patients underwent OGD. The mean age was 40 years and women comprised 63% of the sample. Functional dyspepsia was found in 61% and organic dyspepsia in 39%.Among organic dyspepsia, 18% had erosive oesophagitis and 13% had peptic ulcers. 21(4.2%) cases had gastric adenocarcinoma, 8(1.6%) hadadenocarcinoma esophagus, 8 cases of carcinoma had no alarm symptoms. Prevalence of H. pylori is 39%.
Conclusions:Endoscopy in uninvestigated dyspepsia showed predominance of functional disease, whereas cancer is not an uncommon finding. Organic dyspepsia was associated with H pylori infection, age, male and smoking status.
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2022: 6.012
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