The Screening and Morbidity Pattern of Glucose-6-Phosphate Dehydrogenase Deficiency Anemia in Children in Chhattisgarh

Author: 
Dr. Dushyant, Dr. Lowkesh Chandravanshi and Dr. Satyawati Rathia

Glucose-6-phosphatedehydrogenase (G6PD) deficiency is an X-linked genetic defect, affecting around 400 million people worldwide and is characterized by considerable biochemical and molecular heterogeneity. Deficiency of this enzyme is highly polymorphic in areas where malaria, undernutrition and lack of education are endemic. G6PD deficiency was reported in India more than 50 years ago. Our objective was to find out prevalence of G6PD anemia among the population of Kondagaon districts of Chhattisgarh with clinical and hematological profile of G6PD deficiency patients. According to studies, the prevalence of G6PD deficiency in India ranges between 0.8 and 6.3, with an overall average of around 1.9, with the highest prevalence observed in the tribal populations of certain states like Jharkhand, Chhattisgarh, and Gujarat.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2025.0525.0082