Acupuncture is used as an adjunct therapy throughout the World to treat various chronic ill disorders like systemic hypertension, diabetes. In our study, we investigated the effects of Acu-TENS therapy at Zhongwan (CV12) acupoint in Streptozotocin (45mg/kg/body weight/IP) induced diabetic rats and was compared with anti-diabetic drug (Pioglitazone 7.5mg/kg/body weight). Acu-TENS with low frequency (15HZ), high intensity, pulse width of 5 sec was used to stimulate the Zhongwan acupoint (CV12) for 5 minutes daily without anaesthesia for 60 days. Significant (p≤0.01) decrease in blood glucose level, the total cholesterol, triglycerides, low density lipid and with significant increase in high density lipid. Histopathological examination of pancreatic islets shows increased cellular density in Zhongwan acupoint treated rats and was compared with anti-diabetic drug. The anti-diabetic and lipolytic effect of Zhongwan(CV12) acupoint may be due to increase in insulin secretion through the mediation of β- endorphin.
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2022: 6.012
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