Introduction: Congestive Heart failure is a common cardiovascular condition and a major public health problem. Lactate is an end-product of anaerobic cell metabolism. Brain Natriuretic Peptide is a hormone secreted by the ventricles in the heart as a response to left ventricular stretching or wall tension.
Aim: To evaluate the association of Brain-Natriuretic peptide with Serum lactate levels in Congestive Heart Failure patients.
Materials and Methods: Total 100 diagnosed cases of Congestive Heart Failure, age between 18-65 years of either gender were included. Patients with cardiopulmonary arrest, cardiogenic shock, acute coronary syndrome or infection and other chronic disease were excluded. Total patients were divided into 2 groups on the basis of lactate levels. Group-1 included patients with lactate levels <2.0 mmol/L and Group-2 with lactate levels ≥2.0 mmol/L.
Results and Discussion: The levels of Brain-Natriuretic Peptide were significantly high among patients with lactate levels ≥2.0 mmol/L, when compared with patients had lactate levels <2.0 mmol/L.
Conclusion: Finding of the study suggested that there is a strong correlation between Serum Lactate level and Brain-Natriuretic Peptide level. Screening of Heart Failure patients for these parameters can be helpful in better management of such patients and in averting the risk of mortality.
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