Background: The term‘‘Locomotive Syndrome’’ was introduced by Japanese Orthopaedic Association. They suggestedthat the locomotive syndrome was caused by musculoskeletal diseases to the elderly people. The musculoskeletal organ such as bones, joints and muscles weakening causes this syndrome. This study shows that locomotive syndrome affects the quality of life. Objective: To find the correlation between the timed up and go test and quality of life with locomotive syndrome among community living old age people. Study Design: Non- experimental design, observational type. Procedure: 124 subjects in the age group of 65-75 years of both genders were screened for Locomotive Syndrome using 25- Geriatric locomotive function scale (GLFS-25). Out of 124 subjects, 5 were negative for Locomotive Syndrome. Remaining 119 subjects who were positive for Locomotive Syndrome underwent Timed Up and Go test and Quality of life (QOL) was check using SF-36 Questionnaire. Resuts: There is a significant difference between the timed up and go test and Quality Of Life with locomotive syndrome among community living old age people. Conclusion: This study concluded that significant correlation between the timed up and go test and quality of life with locomotive syndrome among community living old age people.