Background: Lower blood:gas partition coefficient of Sevoflurane and Desflurane facilitates a faster emergence from anaesthesia as compared to traditional agents. Desflurane has demonstrated a rapid early recovery profiles as compared to Sevoflurane. Material and Methods:ASA grade I, II patients, undergoing laparoscopic cholecystectomy were randomly assigned to receive Desflurane (n= 30) or Sevoflurane (n= 30), The time required for extubation, eye opening, verbal response and achievement of a modified Aldrete score of 9 were recorded. Results:The time required for extubation and for eye opening was shorter in the Desflurane group as compared to the Sevoflurane group [12.0±5.0 min versus 14.0±5.0 min and 7.0±4.0 versus 11.0±5.0]. Verbal Response also occurred significantly faster in the Desflurane group [10.0 min ± 4.0 versus12.0±5.0 min]. A modified Aldrete score of ≥9 significantly sooner [13.0±5.0 min versus 19.0±5.0min] than the Sevoflurane group. The frequency of adverse effects was not significantly different in either of the groups. Conclusion: Desflurane has early recovery from anaesthesia as compared to the Sevoflurane group.
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2022: 6.012
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