Introduction: Hypotension is the most common side effect of neuraxial blocks in the obstetric patients. The primary outcome measure of our study was to assess the effect of ephedrine, phenylephrine and mephentermine on maternal hemo-dynamics (hypotension and tachycardia) and the secondary outcome was to see for fetal outcome by comparing APGAR SCORE in the different groups.
Materials and method: A randomized double blinded study was conducted among 96adult patients according to inclusion and exclusion criteria. They were randomlydistributedinto three groups (32 patients each). Group 1patients received 5 mg of intravenousmephentermine, Group 2patients received 5 mg of intravenous ephedrine Group 3 patients received 100 micrograms of intravenous phenylephrine.
Results: In the present study there were least mean number of doses needed in group 3 of 1.13±0.34 and most number in group 1 of 3.69±0.78.APGAR SCORE in all the babies were found to be 9 which was clinically normal. There were no side effects like hypotension, bradycardia or tachycardia noted in any of the patients participated in the study at the end of the surgery.
Conclusion: It is concluded from our study that for immediate control of spinal induced hypotension, phenylephrine is found to be the more effective drug among the study drugs.
Impact Factor
2022: 6.012
This work is licensed under a