Objective: To monitor adverse drug reactions (ADRs) in radiotherapy, paediatrics and ear, nose and throat (ENT) department of a tertiary care teaching hospital.
Materials and Methods: This was a descriptive cross sectional study carried out for detection, classification, assessment and causality analysis of ADRs in radiotherapy, paediatrics and ENT department of a tertiary care teaching institute after approval from Institutional Ethics Committee. The study period was of 22 months from December 2014 to September 2016. Suspected ADRs were recorded in Indian Pharmacopoeia Commission Suspected ADR reporting form.
Results: During study period total 298 patients with ADRs to different drugs were detected. Maximum numbers of ADRs were from department of radiotherapy, followed by ENT and paediatrics department. Maximum ADRs were observed in age group of 41– 60 years with more number of ADRs in female than in male. In causality assessment, maximum ADRs were categorized as probable and maximum ADRs were of moderate severity. GIT was most common system affected followed by skin and CNS. Type A ADRs were found to be commonest.
Conclusion: This study has created a database about different ADRs and the drugs causing it which may be useful in identifying and minimizing ADRs. Various pharmacovigilance awareness programs should be conducted to increase the spontaneous reporting of ADRs. This could help physician to give different prescribing options depending on ADR profile of the drugs; which will ultimately alleviate human sufferings and reduce financial burden to the patient and society.
Impact Factor
2022: 6.012
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