Incidence of esbl, AMPCß-lactamase producing, multi drug resistant and extensively drug resistant acinetobacter spp. in intensive care units of a tertiary care hospital from north india

Background: Acinetobacter spp is an emerging cause of nosocomial infections. These infections are difficult to control and treat because of the increasing antimicrobial resistance worldwide. Objective: To study the incidence of ESBL, AmpC, beta lactamases, MDR, XDR, and PDR Acinetobacter spp. Material and methods: The isolates of Acinetobacter spp. obtained from Blood and body fluid samples received in the department of microbiology over a period of one year were characterized on basis of their sensitivity to various drugs and were further categorized as ESBL or Amp C producers and also MDR,XDR and PDR Results: Out of the 44 Acinetobacter isolates, 38(86.4%) were probable ESBL producers and 3(7.8%) were confirmed ESBL producers. 38(86.4%) of the isolates, were probable AmpC producers, and 20(45.5%) of them were confirmed AmpC producers. Conclusion: The high prevalence of resistance in Acinetobacter isolates emphasizes the need for early detection so that it can help in providing appropriate antimicrobial therapy and also to combat the nosocomial infections.