Study of clinical, haematological profile and outcome in patients with malaria in a tertiary care center

Author: 
Pavani Kiranmayi Munagala, Priyadarshini P and Purushotham Rao B

Malaria is a major vector-borne infection in India and Visakhapatnam district is one of them. The objective of study is to correlate the haematological and clinical profile with the final outcome.
Materials: Patients with Malaria confirmed by Peripheral Smear, Quantitative buffy coat, or Antigen Assay were investigated, examined and followed up at King George Hospital, Visakhapatnam, from January 2018 to December 2018.
Results: Of the 50 patients, 5 had severe anemia. Plasmodium falciparum was the most frequently observed species. 59.25% of the patients with falciparum malaria had splenomegaly. Lymphocytosis was observed in 36% of the patients. Leucopenia was seen in 16%. Neutrophilia occurred in 22% of cases. Thrombocytopenia was observed in 68% of the patients. Prothrombin time was increased in 22% of the total cases.
Conclusions: Severe anaemia was a poor prognostic factor and had an adverse outcome. Thrombocytopenia was commonly seen. Increased bleeding time was associated with high morbidity.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2019.20277.3955
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