Paracetamol is one of the most commonly available over the counter drug used as analgesic and antipyretic. It is considered to be a relatively safe drug. However, some rare cases of Stevens-Johnson syndrome (SJS) have been reported in the past which are thought to be associated with use of paracetamol. SJS is a severe, life-threatening hypersensitivity reaction and requires prolonged hospitalization and intensive care. Here; we present the case of a 21-year-old male who developed SJS after taking a dose of paracetamol.