Plants remain the major source of secondary metabolites. They are used to natural drug for various diseases. In the present study focused on the potential antibacterial and anticancer activities of ethanol bark extracts of Tamarindus indicus. Hence, this study has evaluated the in vitro effects of ethanol bark extracts on human colorectal adenocarcinoma cell line (HT29). The result of present study, the maximum cytotoxicity (94.89 %) and minimum cell viability (5.11 %) were obtained the 500 µg/ml concentrations of ethanol bark extracts of T. indica. For the HT-29 cell line, the 50 % cytotoxicity concentration (CTC50) was found to be 15.6 µg/ml in ethanol extract. Further investigation, the antibacterial activity of ethanol bark extract of T. indica was found to produce a pronounced inhibition of Streptococcus pneumoniae (13mm) followed by Pseudomonas aeruginosa (12 mm), Escherichia coli (11mm), Salmonella typhi (11mm), Klebsiella pneumonia (10 mm) and Bacillus subtilis (10mm) (Table.1). The highest activity was observed in ethanol extract of T.indica against Streptococcus pneumoniae (13mm) and Pseudomonas aeruginosa (12mm). The results suggest that bark extract of T. indica possess the strong antibacterial and anti-cancer activities.
Impact Factor
2022: 6.012
This work is licensed under a