Thyroid eye disease-a clinical hormonal and ultrasonographic evaluation

Introduction: Thyroid eye disease is defined as an autoimmune inflammatory disorder that affects orbital muscles and fat. Although usually associated with hyperthyroidism, Graves’ ophthalmopathy may accompany hypothyroidism or Hashimoto’s thyroiditis. Objective: To evaluate ocular, ultrasonic and hormonal findings in thyroid eye disease. Methodology: This is a study involving 50 patients of various age group with signs and symptoms of thyroid ophthalmology department of Gauhati Medical College and hospital, Guwahati, Assam. Results and observations: Out of 50 patients, bilateral ophthalmopathy was seen in 41 (82%) patients and unilateral in 9 (18%) patients.84% had hyperthyroidism, 4% had hypothyroidism and 12% had euthyroidism. On B scan ultrasonography 62% cases with proptosis had enlarged extraocular muscles, most commonly involving inferior rectus muscle (74%).