A study review of william buren syndrome as a multi systemic disorder and the complication which accompanies

Introduction: William syndrome is a congenital disease which affects multiple systems at the same time. It involves the cardiovascular system, connective tissue, central nervous system, also causes psychological and psychiatric disorders. These populations will be presented with many characteristic facial features, dermatological, gastrointestinal, urogenital and endocrine. They may face complications during anesthesia. This study is a review of previous study showing and I define which complication of each system Williams syndrome can cause.
Conclusion: The review showed the cardiovascular system id the most commonly involved and its association with anesthesia. Fallowed by the neurological, the psychiatric and psychological in the shape of neurological delay, hypotonia, anxiety disorder and hyper sociality respectively. Also cerebellum Through The vermis and the medulla (The swallowing center, the nuclei of the 10th and 9th nerves) they contributes in the swallowing mechanism and the motility of the esophagus. William syndromes individuals will be presented with cerebellar vermis hypoplasia, ventriclomegally, thin corpus callosum, white matter immaturity and posterior fossa cysts all these complications will induce a defect in the esophageal motility. A study showed that hypercalcemia is mostly developed during infantile and early childhood.