Introduction: Diabetes mellitus (DM) refers to a group of common metabolic disorders that share the phenotype of hyperglycemia. It results from defects in insulin secretion, insulin action or both. Diabetes mellitus impairs the metabolism of carbohydrates, proteins, fats, water and electrolytes. These metabolic disturbances lead to permanent and irreversible functional and structural changes in the body which in turn leads to the development of “diabetic complications” affecting, the cardiovascular system, nervous system, renal system and eyes. Diabetes has shown to be associated with abnormalities in the metabolism of any micronutrients. Out of these magnesium has been investigated as a clinically significant electrolyte. Magnesium depletion has a negative impact on glucose homeostasis and insulin sensitivity in patients with type 2 diabetes as well as on the evolution of complications such as retinopathy, arterial atherosclerosis and nephropathy. Hypomagnesemia occurs with an increased frequency among patients with type 2 diabetes as compared with non diabetes according to the previous studies. Hence, this study was undertaken to find the relationship between serum magnesium and diabetic retinopathy, nephropathy and foot ulcers in type 2 diabetes mellitus patients. Materials & Methods: It is an observational study done on 100 patients with diabetic retinopathy, diabetic nephropathy, and diabetic foot ulcer. Results: The serum magnesium levels were low (<1.5 mg/dL) in 72% of the diabetics. The mean serum magnesium levels were 1.32±0.27 mg/dL. Conclusion: In our case study, it was concluded that there is a strong relationship between hypomagnesemia and diabetic complications that is diabetic retinopathy, nephropathy and diabetic foot ulcer.
Impact Factor
2022: 6.012
This work is licensed under a