Pemphigus vulgaris a rare autoimmune disease: a case report

Author: 
Biradar S M., Pooja Bijjaragi., Ummehani M., Pradeepti K, Manjunath Rao., Anand P. Ambali and Kalyane NV

Pemphigus vulgaris (PV) is a potentially life threatening disease that causes erosions and blisters of the skin and mucous membranes. It is a rare disease involve the mucosa and skin through the disintegration of cellular adherence (acantholysis), resulting in intradermal bullous disease. The lesions are usually painful and untreated generalized Pem¬phigus vulgaris may be a fatal one. A 39 year old male patient with known history of Pemphigus vulgaris completed DCP therapy I phase and is on interviewing oral Cyclophosphamide 50mg/day was admitted with chief complaints of new lesions since 2 days over scalp and trunk. Successful implementation of Dexamethasone-Cyclophosphamide-Pulse (DCP) therapy has reduced the mor¬tality rate dramatically along with other adjuvant drugs. Untreated, Pemphigus vulgaris is often fatal because of the susceptibility to infection and fluid-electrolyte disturbances hence, utmost importance to be given for PV treatment.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2018.14099.2544
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