Introduction: Sepsis and its complications are leading causes of mortality. It is becoming an often complication in hospitalized patients. Timely diagnoses and management is very important to reduce incidence of morbidity and mortality. Serum Procalciton in (PCT) levels are elevated in patients with bacterial infections and reported as useful biochemical marker. PCT can be a more accurate diagnostic parameter and reliable marker for sepsis and a better predictor of mortality.
Aim: To evaluate the level of Serum PCT in patients diagnosed for sepsis.
Material & Method: Total 75 subjects enrolled for the study were categorised on the basis of severity among three groups, Sepsis (n=25), Severe Sepsis (n=25) and Septic Shock (n=25). Serum PCT levels and other parameters were estimated for all enrolled subjects according to inclusion criteria. The results obtained were presented as mean ± SD and subjected to statistical evaluation. A p-value of ≤0.05 was considered statistically significant.
Result: Mean levels of PCT were found to be significantly increased in sepsis, severe sepsis and septic shock patients with p-value 0.0005.
Conclusion: The study suggests a strong correlation between severity of sepsis and PCT. The study further recommends evaluation of association of sepsis cause with the above markers.
Impact Factor
2022: 6.012
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