Introduction: The present study was undertaken with an aim to compare the intubating conditions, onset time, haemodynamic effects and adverse effects with the use of atracurium, cisatracurium and rocuroniumto develop a non-depolarising muscle relaxant with a speed of onset comparable with succinylcholine but with less adverse effects.
Materials and Methods: A randomized double blinded study was conducted among 75 adult patients according to inclusion and exclusion criteria. They were randomly distributed into three groups (25 patients each). Group I received 0.6mg/kg rocuronium, group II received 0.1mg/kg cisatracurium and group III received 0.5 mg /kg atracurium intravenous injection. To assess the intubating condition and the onset of action of different drugs, a Train of four monitor was used.
Results: The mean onset time of action was fastest in group I(89.28+5.53 seconds with intubating condition score of 8.68) than group II and group III. All three groups had similar or comparable haemodynamic response after intubation. There were no side effects recorded.
Conclusion: From the study, it could be concluded that rocuronium at a dose of 0.6 mg/kg provides better intubating condition than atracurium and cisatracurium.
Impact Factor
2022: 6.012
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