Diabetic ulcers are the most frequent reason for hospitalization in patients with diabetes. Currently, a lot of attention is being placed on the development of expensive topical growth factors for wound healing. Thus, there remains a quest for better wound healing agents. One such agent is phenytoin, which is cheap, easy to use and readily available for medical practice. The aim of the study is to compare the efficacy of topical phenytoin with saline and normal saline in healing of diabetic ulcers, in terms of days required for healing, rate of granulation tissue formation, quality of graft bed, graft uptake, effect on bacterial growth and side effects of topical phenytoin. we carried out our study in 2 groups 50 each, Saline and Phenytoin sodium(SP) group and Normal Saline(NS) in our institute. The number of days was 31.3 in group NS and 27.88 in group SP to heal. Negative bacterial growth in NS group was 37, while 45 in SP group. Graft uptake was seen in 37 cases in NS group, while it was 40 in SP group, which were statistically significant. So, we concluded that saline and phenytoin have a good effect than normal saline in diabetic wound dressing.
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2022: 6.012
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