Association between 25-hydroxyvitamin d level and type 2 diabetes among adult employees

Introduction: Increasing evidence suggests that Vitamin Dplays a function in the progress of chronic diseases includingtype 2 diabetes (DM). Aim of the work: was to explore the association of Vitamin Dlevels with widely wide-spread DM in a sample of predominantly healthful working adults more than 45 of age. Subjects and Methods: This cross-sectional Study (2016-2017) involved 823 at 9 working sites in different governorates, Egypt (83.2% male, mean age 51.8 ±5.5 years). Sociodemographic and medical history had been assessed by self-report. Scientific characteristics have been got including blood samples to check vitamin D levels and diabetes status by means of fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c). Vitamin Dwas grouped into considered one of 4 categories (<10 ng/ml, 10-19.9 ng/ml, 20-29.9 ng/ml, ≥30 ng/ml). Bivariate associations betweenvitaminD levels and a composite indicator for DM (FPG ≥126 mg/dl or HbA1c ≥6.5% or self-reporteddiagnosis) had been calculated; multivariable units confirmed this association further, controlling for expertise confounders. Results: severe vitamin D deficiency (<10 ng/ml) was related to growing FPG (β 3.14; 95%CI: 0.78, 5.48; p≤0.01) and HbA1c (β 0.15; 95%CI: 0.08, 0.24; p≤0.001) values in adjusted linear regression models. In multivariable models, severVitamin Ddeficiency used to be associated with DM (OR 2.54; 95%CI 1.16, 5.63; p≤0.05) after controlling for abilities confounders. Conclusions: vitaminD deficiency is associated with widespread DM in working adults. The findings spotlight that the workplace is also a targeted location for conducting big-scale health screening to establish these at risk of DM making use of vitamin D.