Appraisal of signs and symptoms, clinical outcomes in neonatal sepsis-a prospective observational study

Author: 
Karishma Shaik., Sai Lakshmi Bhavani Pusuluri. , Madhuri Para., Greeshma Musunuru., N.V.Rama Rao., M.S. Raju and Rama Rao Nadendla

Background- Sepsis remains a major cause of morbidity and mortality among neonates. Early-onset sepsis is associated with acquisition of microorganisms from the mother. Transplacental infection or an ascending infection from the cervix may be caused by organisms that colonize the mother’s genitourinary (GU) tract. It occurs at 0-3 days of life.. Late onset sepsis is related to hospital acquired infections. The purpose of this study was to assess clinical outcomes and signs and symptoms of neonatal sepsis.
Results- Based on our study it is found that in signs and symptoms the Fever which is clinically significant and remaining signs and symptoms are clinically non significant. Out of 26 culture positive cases Discharge cases were 15(58%), Left Against Medical Advice cases were 4(15%) and Death were 7(27%). Out of clinical sepsis cases, Discharge cases were 70(58%), Left Against Medical Advice cases were 13(11%) and Death were 37(31%).
Conclusion- Most commonly seen symptoms are lethargy, poor cry, activity, respiratory distress, poor rooting and icterus. In spite of presence number of patients who were cured and get discharged, there is a considerable amount of deaths.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2019.3843.19788
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