Periodontal disease is characterized by the destruction of periodontal tissues including periodontal ligament, alveolar bone and cememtum with subsequent loss of tooth. Conventional open flap debridement provides an access to evaluate and detoxify root surface as well as to improve periodontal form and architecture. Periodontal regenerative therapy aimed at regeneration of lost periodontal tissue with the help of use of barrier membranes, bone replacement grafts, growth factors and the combination of these procedures have been investigated. Bone replacement grafts include autografts, allografts, xenografts and allografts. These graft materials are being widely used to promote new bone formation and periodontal regeneration in periodontal therapy. This article reviews various synthetic bone substitutes available for clinical applications used for periodontal regeneration.
Impact Factor
2022: 6.012
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